This is a question I've been asked more than once so I figure it's time for a thread. Standard Disclaimer: Always seek professional medical care when sustaining a wound bad enough to require closure, however if you're in the field this is a good technique to get you home without using potentially harmful techniques such as tape, field suturing, etc... A warning about mastisol if you decide to buy it, make sure to dab a drop or two on your skin and leave it for at least a day or more before you try it on a wound. Some people are very allergic and the local reaction can complicate the wound healing. I see it in about 1 in 200 patients I use it on. In a nutshell, just place a 1 cm wide stripe of mastisol about 1cm from the wound margin parallel with the wound. Then let the adhesive dry for about 20 seconds and run the Steri-Strips across the wound to keep it closed. Do not create too much tension when applying the strips or you will cause the skin to break down and blister. What I do is adhere one side of the strip and gently pull the wound closed and then apply the other side, this is usually sufficient to close the wound without much tension. This works with most wounds but if it's a large "gaping" wound you won't be able to close it like this. That is why when we suture it must be done in multiple layers. Be sure to clean/irrigate the area thoroughly and and disinfect the skin. I consider this combination one of the most important and commonly used items in my first aid kit. How to apply mastisol: https://www.youtube.com/watch?v=oHwsVYnP42Q How to apply Steri-Strips: https://www.youtube.com/watch?v=C5m0CYCt59E (If using mastisol it is not necessary to add the second set of strips that runs parallel to the wound) Found on Amazon here: http://www.amazon.com/Mastisol-Medical-Liquid-Adhesive-Vials/dp/B006TKM2JC# (I highly recommend the ampules since they stay sterile and can easily be kept in a first aid kit) If you are allergic or cannot use mastisol then benzoin also works but doesn't hold as well in my opinion. Mastisol is a far superior adhesive and is more resistant to wear and moisture. I carry and recommend this brand and size of Steri-Strips: 3M Steri Strip Skin Closures 1/4'' X 3'' -Package of 3 http://www.amazon.com/3M-Steri-Strip-Skin-Closures/dp/B00BMU6CWW/ref=sr_1_1?ie=UTF8&qid=1408298190&sr=8-1&keywords=3M+steri-strips 3M Steri-Strip Skin Closures 1/2" x 4" -Package of 6 http://www.amazon.com/3M-Steri-Strip-reinforced-Skin-Closures/dp/B004WFXCSQ/ref=sr_1_2?ie=UTF8&qid=1408298190&sr=8-2&keywords=3M+steri-strips Look around and you can find different quantities and prices, these are just examples I found. If you only want to have one size then go with 1/4x3" I use these the most. The 1/2x4" is for larger wounds/longer wounds.